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[AHA2011]ω-3脂肪酸对心血管疾病预防和治疗作用——Michael Davidson教授 专访

作者:  MichaelDavidson   日期:2011/11/16 19:22:40

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<International Circulation>: We know that omega-3 fatty acids have been around for about 30 years now. Can you tell us about some of the benefits of omega-3 fatty acids on cardiovascular disease prevention and treatment?

    <International Circulation>:    In your talk you said that a new form of free omega-3 fatty acid produced a four-fold higher bioavailability than traditional ether-esters.  Are there any safety issues concerning those high concentration omega-3 fatty acids?

  《国际循环》:在您的谈话中,您曾说过自由ω- 3脂肪酸的的一种新形式的生物利用度比传统醚酯高4倍,考虑到如此高浓度的ω- 3脂肪酸,是否存在安全问题?
 
    Prof. Davidson: No, not at all.  In our research we have looked at populations like the Greenland Eskimos who are eating much higher levels of omega-3 fatty acids and they do not have any heart disease.  We think we need to give enough to have an effect, 4 grams of free omega-3 fatty acid, which is considered to be recognized as a safe level both in the United States and throughout the world.  It is not a lot of omega-3 fatty acids but in other less bioavailable forms, to give a lot of it, a person would have to eat something like 10 or 20 capsules.  In this form giving 2 or 3 capsules of the free fatty acids might be high enough of a dose because it is so better absorbed to provide a lot of the clinical benefits for patients to prevent heart disease or to treat cardiovascular disease.

    Davidson教授:并非如此。在我们的研究中,我们已经观察到跟格陵兰岛的爱斯基摩人一样的人群中食用的ω- 3脂肪酸的水平要高得多,他们没有任何心脏疾病。我们认为我们需要提供足够的ω- 3脂肪酸才能起作用。4g的自由ω- 3脂肪酸,对于美国以及全世界的人来说都是一个安全的水平。ω- 3脂肪酸生物利用度较低的其他形式,含量也不多,因此需要大量服用,一个人需要服用其他比如10或20个胶囊。以这种给予2或3个胶囊的自由脂肪酸可能剂量已足够,因为吸收后效果很好,可以预防心脏疾病或治疗心血管疾病,为患者提供很多临床获益。
 
    <International Circulation>:   So you think it is the more the better?

  《国际循环》:因此您认为它越多越好?
 
    Prof. Davidson: The more the better I’m not so sure.  Certainly, we see that it is necessary to give enough.  People usually cannot get enough by eating a lot of fish.  It really is necessary to take the supplements when it comes to omega-3 fatty acid levels in the blood.

    Davidson教授:越多越好我并不确定。当然,我们看到有必要给足。人们往往吃了很多余也不能得到足够的ω- 3脂肪酸。为了血液中ω- 3脂肪酸的水平,确实又必要服用补充剂。
 

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ω-3脂肪酸心血管疾病高脂血症Michael Davidson

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